Perineural Injection Therapy (PIT)
What Is PIT
Perineural Therapy Explained
Perineural therapy (also known as Lyftogt Perineural Injection Treatment®) is a gentle, minimally-invasive approach developed to calm irritated sensory nerves just beneath the skin that can contribute to chronic and neuropathic pain. It involves a series of small injections of a buffered dextrose (glucose) solution into areas where nerves are sensitive, with the goal of reducing nerve-related inflammation and pain and helping restore normal function over time.
Unlike traditional pain management that simply masks symptoms, this method works on the peripheral nerves themselves, typically using weekly treatments over several sessions to gradually diminish pain and improve function.
The solution used in perineural therapy is drug-free and safe—D5W (5% dextrose in sterile water) is commonly used in medical settings—and the technique is designed to be low-risk and well-tolerated.
FAQs - Perineural Injection Therapy
Perineural Injection Therapy – Frequently Asked Questions
1. What is perineural injection therapy?
Perineural injection therapy is a gentle treatment that targets irritated superficial nerves just under the skin using small injections of a dextrose (glucose) solution to reduce nerve inflammation and pain.
2. What conditions can perineural therapy help with?
It is commonly used for back and neck pain, migraines and headaches, nerve irritation, joint pain, tendon pain, chronic pain, and pain related to nerve hypersensitivity.
3. How does perineural therapy work?
The injections help calm inflamed sensory nerves that send pain signals to the brain. By reducing this irritation, nerve function can normalize and pain can decrease over time.
4. What is injected during treatment?
A dilute solution of dextrose mixed with sterile water is used. It is not a steroid, anesthetic, or medication.
5. Is perineural injection therapy safe?
Yes. The solution used is commonly found in medical settings and treatments are considered low risk when performed by a trained practitioner.
6. Does the treatment hurt?
Most patients tolerate it very well. The injections are superficial and use very small needles. Some people feel mild stinging or pressure that typically resolves quickly.
7. How many treatments will I need?
This varies depending on the condition and how long symptoms have been present. Many people benefit from a series of treatments spaced over several weeks.
8. How quickly will I notice results?
Some patients notice improvement after the first session, while others experience gradual improvement over multiple treatments as nerve irritation settles.
9. Are there side effects or downtime?
Side effects are usually minimal and may include temporary redness, swelling, or soreness at injection sites. There is little to no downtime, and most people resume normal activities the same day.
10. How is perineural therapy different from other pain treatments?
Rather than masking pain with medications or suppressing inflammation with steroids, perineural therapy focuses on calming irritated nerves and addressing one of the root contributors to chronic pain.